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#
# You can remove the examples below
@article{Batut2018,
doi = {10.1016/j.cels.2018.05.012},
url = {https://doi.org/10.1016/j.cels.2018.05.012},
year = {2018},
month = jun,
publisher = {Elsevier {BV}},
volume = {6},
number = {6},
pages = {752--758.e1},
author = {B{\'{e}}r{\'{e}}nice Batut and Saskia Hiltemann and Andrea Bagnacani and Dannon Baker and Vivek Bhardwaj and
Clemens Blank and Anthony Bretaudeau and Loraine Brillet-Gu{\'{e}}guen and Martin {\v{C}}ech and John Chilton
and Dave Clements and Olivia Doppelt-Azeroual and Anika Erxleben and Mallory Ann Freeberg and Simon Gladman and
Youri Hoogstrate and Hans-Rudolf Hotz and Torsten Houwaart and Pratik Jagtap and Delphine Larivi{\`{e}}re and
Gildas Le Corguill{\'{e}} and Thomas Manke and Fabien Mareuil and Fidel Ram{\'{i}}rez and Devon Ryan and
Florian Christoph Sigloch and Nicola Soranzo and Joachim Wolff and Pavankumar Videm and Markus Wolfien and
Aisanjiang Wubuli and Dilmurat Yusuf and James Taylor and Rolf Backofen and Anton Nekrutenko and Bj\"{o}rn Gr\"{u}ning},
title = {Community-Driven Data Analysis Training for Biology},
journal = {Cell Systems}
@article{Ayres1994,
title = {The Complete DNA Sequence of Autographa californica Nuclear Polyhedrosis Virus},
volume = {202},
ISSN = {0042-6822},
url = {http://dx.doi.org/10.1006/viro.1994.1380},
DOI = {10.1006/viro.1994.1380},
number = {2},
journal = {Virology},
publisher = {Elsevier BV},
author = {Ayres, Martin D. and Howard, Stephen C. and Kuzio, John and Lopez-Ferber, Miguel and Possee, Robert D.},
year = {1994},
month = aug,
pages = {586–605}
}

@article{vanOers2007,
title = {Baculovirus Genomics},
volume = {8},
ISSN = {1389-4501},
url = {http://dx.doi.org/10.2174/138945007782151333},
DOI = {10.2174/138945007782151333},
number = {10},
journal = {Current Drug Targets},
publisher = {Bentham Science Publishers Ltd.},
author = {van Oers, Monique and Vlak, Just},
year = {2007},
month = oct,
pages = {1051–1068}
@article{Cox2021,
title = {Innovations in the Insect Cell Expression System for Industrial Recombinant Vaccine Antigen Production},
volume = {9},
ISSN = {2076-393X},
url = {http://dx.doi.org/10.3390/vaccines9121504},
DOI = {10.3390/vaccines9121504},
number = {12},
journal = {Vaccines},
publisher = {MDPI AG},
author = {Cox, Manon M. J.},
year = {2021},
month = dec,
pages = {1504}
}

@article{Fan2020,
Expand All @@ -63,34 +58,6 @@ @article{Fan2020
month = sep
}

@article{Wennmann2024,
title = {Haplotype determination of the Bombyx mori nucleopolyhedrovirus by Nanopore sequencing and linkage of single nucleotide variants},
volume = {105},
ISSN = {1465-2099},
url = {http://dx.doi.org/10.1099/jgv.0.001983},
DOI = {10.1099/jgv.0.001983},
number = {5},
journal = {Journal of General Virology},
publisher = {Microbiology Society},
author = {Wennmann, J\"{o}rg T. and Lim, Fang-Shiang and Senger, Sergei and Gani, Mudasir and Jehle, Johannes A. and Keilwagen, Jens},
year = {2024},
month = may
}

@misc{ICTV_AcMNPV_genome_figure,
author = {International Committee on Taxonomy of Viruses (ICTV)},
title = {Genome mag of Autographa californica multiple nucleopolyhedrovirus isolate C6 (Figure 2)},
url = {\url{https://ictv.global/sites/default/files/inline-images/7651.ODD.Baculo.Fig2.v2.png}},
urldate = {2024-12-27}
}

@online{gtn-website,
author = {GTN community},
title = {GTN Training Materials: Collection of tutorials developed and maintained by the worldwide Galaxy community},
url = {https://training.galaxyproject.org},
urldate = {2021-03-24}
}

@article{Harrison2018,
title = {ICTV Virus Taxonomy Profile: Baculoviridae},
volume = {99},
Expand All @@ -106,29 +73,33 @@ @article{Harrison2018
pages = {1185–1186}
}

@article{Ayres1994,
title = {The Complete DNA Sequence of Autographa californica Nuclear Polyhedrosis Virus},
volume = {202},
ISSN = {0042-6822},
url = {http://dx.doi.org/10.1006/viro.1994.1380},
DOI = {10.1006/viro.1994.1380},
@article{RodrguezHernndez2023,
title = {Baculovirus Display of Peptides and Proteins for Medical Applications},
volume = {15},
ISSN = {1999-4915},
url = {http://dx.doi.org/10.3390/v15020411},
DOI = {10.3390/v15020411},
number = {2},
journal = {Virology},
publisher = {Elsevier BV},
author = {Ayres, Martin D. and Howard, Stephen C. and Kuzio, John and Lopez-Ferber, Miguel and Possee, Robert D.},
year = {1994},
month = aug,
pages = {586–605}
journal = {Viruses},
publisher = {MDPI AG},
author = {Rodríguez-Hernández, Aaron Pavel and Martínez-Flores, Daniel and Cruz-Reséndiz, Adolfo and Padilla-Flores, Teresa and González-Flores, Rodrigo and Estrada, Kenia and Sampieri, Alicia and Camacho-Zarco, Aldo Román and Vaca, Luis},
year = {2023},
month = feb,
pages = {411}
}

@misc{sequence-analysis-quality-control,
author = "Bérénice Batut and Maria Doyle and Alexandre Cormier and Anthony Bretaudeau and Laura Leroi and Erwan Corre and Stéphanie Robin and Cameron Hyde",
title = "Quality Control (Galaxy Training Materials)",
year = "",
month = "",
day = "",
url = "\url{https://training.galaxyproject.org/training-material/topics/sequence-analysis/tutorials/quality-control/tutorial.html}",
note = "[Online; accessed Wed Jan 08 2025]"
@article{vanOers2011,
title = {Opportunities and challenges for the baculovirus expression system},
volume = {107},
ISSN = {0022-2011},
url = {http://dx.doi.org/10.1016/j.jip.2011.05.001},
DOI = {10.1016/j.jip.2011.05.001},
journal = {Journal of Invertebrate Pathology},
publisher = {Elsevier BV},
author = {van Oers, Monique M.},
year = {2011},
month = jul,
pages = {S3–S15}
}

@article{Wennmann2020,
Expand All @@ -144,4 +115,50 @@ @article{Wennmann2020
year = {2020},
month = jun,
pages = {625}
}

@article{Wennmann2024,
title = {Haplotype determination of the Bombyx mori nucleopolyhedrovirus by Nanopore sequencing and linkage of single nucleotide variants},
volume = {105},
ISSN = {1465-2099},
url = {http://dx.doi.org/10.1099/jgv.0.001983},
DOI = {10.1099/jgv.0.001983},
number = {5},
journal = {Journal of General Virology},
publisher = {Microbiology Society},
author = {Wennmann, J\"{o}rg T. and Lim, Fang-Shiang and Senger, Sergei and Gani, Mudasir and Jehle, Johannes A. and Keilwagen, Jens},
year = {2024},
month = may
}

@inbook{Eberle2012,
title = {Microbial control of crop pests using insect viruses.},
ISBN = {9781780640020},
url = {http://dx.doi.org/10.1079/9781845938086.0281},
DOI = {10.1079/9781845938086.0281},
booktitle = {Integrated pest management: principles and practice},
publisher = {CABI},
author = {Eberle, K. E. and Jehle, J. A. and Huber, J.},
year = {2012},
month = jan,
pages = {281–298}
}

@inbook{Grzywacz2017,
title = {Production, Formulation, and Bioassay of Baculoviruses for Pest Control},
ISBN = {9780128035276},
url = {http://dx.doi.org/10.1016/B978-0-12-803527-6.00007-X},
DOI = {10.1016/b978-0-12-803527-6.00007-x},
booktitle = {Microbial Control of Insect and Mite Pests},
publisher = {Elsevier},
author = {Grzywacz, D. and Moore, S.},
year = {2017},
pages = {109–124}
}

@misc{ICTV_AcMNPV_genome_figure,
author = {International Committee on Taxonomy of Viruses (ICTV)},
title = {Genome mag of Autographa californica multiple nucleopolyhedrovirus isolate C6 (Figure 2)},
url = {\url{https://ictv.global/sites/default/files/inline-images/7651.ODD.Baculo.Fig2.v2.png}},
urldate = {2024-12-27}
}
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# Introduction

Baculoviruses of the family *Baculoviridae* ({% cite Harrison2018 %}) are among the most intensively
studied viruses, not only because of their widespread application in biotechnology, medicine, and
agriculture ({% cite vanOers2007 %}). Like all members of the class *Naldaviricetes*,
studied viruses, not only because of their widespread application in biotechnology as protein expression
systems, medicine, and as biological insecticides ({% cite RodrguezHernndez2023 %},
{% cite Cox2021 %}, {% cite Grzywacz2017 %}, {% cite Eberle2012 %}, {% cite vanOers2011 %}).
Like all members of the class *Naldaviricetes*,
baculoviruses have large circular dsDNA genomes that, in the family *Baculoviridae*,
range from 90 to 180 kbp and can encode up to 180 open reading frames (ORFs).
A detailed description of the biology of the Baculoviridae family can be found in the
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