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remomomo authored Jul 27, 2022
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# Functional Annotation and Association Testing Pipeline
Pipeline to run variant effect prediction and rare-variant association tests for continuous phenotypes on UK Biobank exome sequencing (or other) data. It uses [Snakemake](https://snakemake.github.io/) to parallelize large parts of the analysis across chromosomes and phenotypes. Conda on a Linux system is the main requirement for getting started.

This pipeline was originally run on different virtual machines in local mode. For full cluster support, users can easily modify `./run.sh` to use SLURM, SGE or other schedulers with Snakemake.
This pipeline was originally run on different virtual machines in local mode. A snakemake profile for slurm is provided at `./slurm`.

## Getting Started
### Installing basic dependencies
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