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DESCRIPTION
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Package: bbum
Title: BBUM correction for significance testing of p values
Version: 1.1
Authors@R:
person(given = "Peter Y.",
family = "Wang",
role = c("aut", "cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0002-6129-2815",
Advisor = "David P. Bartel"))
Description: Standard multiple testing correction methods are not sufficient to
directly handle datasets that contain a weaker background secondary signal
confounding the primary signal of interest. This package describes and
applies the bi-beta-uniform mixture (BBUM) model to adjust p-values. It
allows a modified estimation of false discovery rate (FDR) that takes into
consideration the secondary signal in the background that needs to be
excluded.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Imports:
data.table (>= 1.14.0),
dplyr (>= 1.0.7),
ggplot2 (>= 3.3.5),
magrittr (>= 2.0.1),
purrr (>= 0.3.4),
tibble (>= 3.1.4),
tidyr (>= 1.1.3)
URL: https://github.com/wyppeter/bbum
BugReports: https://github.com/wyppeter/bbum/issues