diff --git a/Sources/Dependencies/DependencyValues.swift b/Sources/Dependencies/DependencyValues.swift
index eda32d55..889795c3 100644
--- a/Sources/Dependencies/DependencyValues.swift
+++ b/Sources/Dependencies/DependencyValues.swift
@@ -268,6 +268,10 @@ public struct DependencyValues: Sendable {
     }
     set {
       if DependencyValues.isPreparing {
+        if context == .preview, Thread.isPreviewAppEntryPoint {
+          reportIssue("Ignoring dependencies prepared in preview app entry point")
+          return
+        }
         let cacheKey = CachedValues.CacheKey(id: TypeIdentifier(key), context: context)
         guard !cachedValues.cached.keys.contains(cacheKey) else {
           if cachedValues.cached[cacheKey]?.preparationID != DependencyValues.preparationID {
@@ -547,6 +551,9 @@ public final class CachedValues: @unchecked Sendable {
         case .live:
           value = (key as? any DependencyKey.Type)?.liveValue as? Key.Value
         case .preview:
+          if Thread.isPreviewAppEntryPoint {
+            return Key.previewValue
+          }
           if !CachedValues.isAccessingCachedDependencies {
             value = CachedValues.$isAccessingCachedDependencies.withValue(true) {
               #if canImport(SwiftUI) && compiler(>=6)
diff --git a/Sources/Dependencies/Internal/AppEntryPoint.swift b/Sources/Dependencies/Internal/AppEntryPoint.swift
new file mode 100644
index 00000000..4b66109b
--- /dev/null
+++ b/Sources/Dependencies/Internal/AppEntryPoint.swift
@@ -0,0 +1,30 @@
+import Foundation
+
+extension Thread {
+  public static var isPreviewAppEntryPoint: Bool {
+    guard ProcessInfo.processInfo.environment["XCODE_RUNNING_FOR_PREVIEWS"] == "1"
+    else { return false }
+
+    var isPreviewAppEntryPoint = false
+    for frame in callStackSymbols.reversed() {
+      if !isPreviewAppEntryPoint, frame.containsSymbol("$s7SwiftUI3AppPAAE4mainyyFZ") {
+        isPreviewAppEntryPoint = true
+      } else if isPreviewAppEntryPoint,
+        frame.containsSymbol("$s7SwiftUI6runAppys5NeverOxAA0D0RzlF")
+      {
+        return false
+      }
+    }
+    return isPreviewAppEntryPoint
+  }
+}
+
+extension String {
+  fileprivate func containsSymbol(_ symbol: String) -> Bool {
+    utf8
+      .reversed()
+      .drop(while: { (48...57).contains($0) })
+      .dropFirst(3)
+      .starts(with: symbol.utf8.reversed())
+  }
+}