[NTR] S cell

[dosumis]

Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label
S cell

Synonyms (add reference(s), please)

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)

An enteroendocrine cell of the small intestine that secretes Secretin into the bloodstream in response to increased luminal pH. These cells have slim apical processes with pH receptors and chemoreceptors that can detect nutrient levels. They are found scattered throughout the epithelial lining of the small intestine, with highest concentrations in the duodenum and jejunum.

https://www.perplexity.ai/search/give-me-details-of-the-structu-eFRGpDZlRbSxGuGk_j9bzg
https://www.perplexity.ai/search/system-role-you-are-a-knowledg-M_qeiaXmTvuWTZoCxpPJJw

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)

enteroendocrine cell

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)
smalll intestine epithelium

Your ORCID

Additional notes or concerns

Poss additional GO term for secretin secretion
GO term for pH detection
GO term for detection of chemical stimulus.

[dosumis]

UPDATE: RECENT PAPER QUESTIONS THIS CATEGORY (and other enteroendocrine categories too): https://www.nature.com/articles/s41598-024-63699-0