The dms_variants package is designed to aid in the analysis of deep mutational scanning of barcoded variants of genes.
It contains many Python functions and classes that you can use in scripts or Jupyter notebooks.
Major functionality includes:
- The :class:`dms_variants.codonvarianttable.CodonVariantTable` class for managing and analyze libraries of barcoded codon variants of genes.
- The :class:`dms_variants.illuminabarcodeparser.IlluminaBarcodeParser` for easily parsing Illumina barcode sequencing that counts variants.
- The :mod:`dms_variants.globalepistasis` module for fitting global epistasis models to experiments on variants with multiple mutations.
Below are a series of examples that illustrate usage of this functionality and other aspects of the dms_variants package.
.. toctree:: :maxdepth: 1 codonvariant_sim_data codonvariant_sim_data_w_gaps codonvariant_sim_data_multi_targets prob_escape parsebarcodes_sim_data narrow_bottleneck codonvariant_plot_formatting
The above examples can be run as interactive Jupyter notebooks on mybinder by going to the following link (it may take a minute to load) and then opening the notebook you want to run.