diff --git a/src/c/CMakeLists.txt b/src/c/CMakeLists.txt
index 385cb658..543a7e23 100644
--- a/src/c/CMakeLists.txt
+++ b/src/c/CMakeLists.txt
@@ -14,6 +14,11 @@ if("${CMAKE_CXX_COMPILER_ID}" STREQUAL "Clang")
     # require at least Clang 9.0
     if (CMAKE_CXX_COMPILER_VERSION VERSION_LESS 9.0)
         message(FATAL_ERROR "Clang++ version must be at least 9.0!")
+    elseif (CMAKE_CXX_COMPILER_VERSION VERSION_GREATER 11)
+        set(PERFFLOWASPECT_CLANG_11_NEWER TRUE CACHE BOOL "using >=clang11")
+        add_definitions(-DPERFFLOWASPECT_CLANG_11_NEWER)
+    elseif (CMAKE_CXX_COMPILER_VERSION VERSION_LESS 11)
+        set(PERFFLOWASPECT_CLANG_11_NEWER FALSE CACHE BOOL "using >=clang11")
     endif()
 else()
     message(WARNING "Unsupported CXX compiler: please use Clang >= 9.0")
diff --git a/src/c/host-configs/lassen-4.14.0-ppc64le-clang@10.0.1-gcc@8.3.1.cmake b/src/c/host-configs/lassen-4.14.0-ppc64le-clang@10.0.1-gcc@8.3.1.cmake
index 37f3db28..f74cf58f 100644
--- a/src/c/host-configs/lassen-4.14.0-ppc64le-clang@10.0.1-gcc@8.3.1.cmake
+++ b/src/c/host-configs/lassen-4.14.0-ppc64le-clang@10.0.1-gcc@8.3.1.cmake
@@ -9,3 +9,4 @@
 ##############################################################
 
 set(CMAKE_CXX_COMPILER "/usr/tce/packages/clang/clang-10.0.1-gcc-8.3.1/bin/clang++" CACHE PATH "")
+set(LLVM_DIR "/usr/tce/packages/clang/clang-ibm-10.0.1-gcc-8.3.1/lib/cmake/llvm" CACHE PATH "")
diff --git a/src/c/host-configs/quartz-4.18.0-x86_64-clang@14.0.6.cmake b/src/c/host-configs/quartz-4.18.0-x86_64-clang@14.0.6.cmake
new file mode 100644
index 00000000..baee2638
--- /dev/null
+++ b/src/c/host-configs/quartz-4.18.0-x86_64-clang@14.0.6.cmake
@@ -0,0 +1,12 @@
+##############################################################
+# Copyright 2021 Lawrence Livermore National Security, LLC
+# (c.f. AUTHORS, NOTICE.LLNS, COPYING)
+#
+# This file is part of the Flux resource manager framework.
+# For details, see https://github.com/flux-framework.
+#
+# SPDX-License-Identifier: LGPL-3.0
+##############################################################
+
+set(CMAKE_CXX_COMPILER "/usr/tce/packages/clang/clang-14.0.6/bin/clang++" CACHE PATH "")
+set(LLVM_DIR "/usr/tce/packages/clang/clang-14.0.6/lib/cmake/llvm" CACHE PATH "")
diff --git a/src/c/test/CMakeLists.txt b/src/c/test/CMakeLists.txt
index 26f7fa05..a57bbb0f 100644
--- a/src/c/test/CMakeLists.txt
+++ b/src/c/test/CMakeLists.txt
@@ -9,7 +9,7 @@ set(SMOKETESTS
 
 find_package(MPI REQUIRED)
 find_package(Threads REQUIRED)
-find_package(CUDA REQUIRED)
+find_package(CUDA)
 include_directories(${MPI_INCLUDE_PATH})
 
 set(perfflow_deps "-L../runtime -lperfflow_runtime -lcrypto")
@@ -25,17 +25,21 @@ foreach(TEST ${SMOKETESTS})
     target_link_libraries(${TEST} ${perfflow_deps})
 endforeach()
 
-message(STATUS " [*] Adding test: smoketest_cuda")
-set(CUDA_NVCC_FLAGS  "-ccbin ${CMAKE_CXX_COMPILER} -Xcompiler=-Xclang -Xcompiler=-load -Xcompiler=-Xclang -Xcompiler=../../../weaver/weave/libWeavePass.so")
-cuda_add_executable(smoketest_cuda smoketest_cuda_wrapper.cpp smoketest_cuda_kernel.cu)
-target_link_libraries(smoketest_cuda ${perfflow_deps} ${CUDA_LIBRARIES} cuda)
+if(CUDA_FOUND)
+    message(STATUS " [*] Adding test: smoketest_cuda")
+    set(CUDA_NVCC_FLAGS  "-ccbin ${CMAKE_CXX_COMPILER} -Xcompiler=-Xclang -Xcompiler=-load -Xcompiler=-Xclang -Xcompiler=../../../weaver/weave/libWeavePass.so")
+    cuda_add_executable(smoketest_cuda smoketest_cuda_wrapper.cpp smoketest_cuda_kernel.cu)
+    target_link_libraries(smoketest_cuda ${perfflow_deps} ${CUDA_LIBRARIES} cuda)
+endif()
 
 configure_file(t0001-cbinding-basic.t.in
     ${CMAKE_CURRENT_BINARY_DIR}/t0001-cbinding-basic.t
     @ONLY)
 
-install(TARGETS ${SMOKETESTS} smoketest_cuda
-        DESTINATION test)
+if(CUDA_FOUND)
+    install(TARGETS ${SMOKETESTS} smoketest_cuda
+            DESTINATION test)
+endif()
 
 install(PROGRAMS ${CMAKE_CURRENT_BINARY_DIR}/t0001-cbinding-basic.t
         DESTINATION test)
diff --git a/src/c/weaver/weave/perfflow_weave.cpp b/src/c/weaver/weave/perfflow_weave.cpp
index edae7b2b..dffd693a 100644
--- a/src/c/weaver/weave/perfflow_weave.cpp
+++ b/src/c/weaver/weave/perfflow_weave.cpp
@@ -12,7 +12,11 @@
 #include "llvm/IR/Attributes.h"
 #include "llvm/IR/Constants.h"
 #include "llvm/IR/LegacyPassManager.h"
+#ifdef PERFFLOWASPECT_CLANG_11_NEWER
+#include "llvm/IR/AbstractCallSite.h"
+#else
 #include "llvm/IR/CallSite.h"
+#endif
 #include "llvm/IR/Module.h"
 #include "llvm/IR/Argument.h"
 #include "llvm/IR/IRBuilder.h"