diff --git a/setup.py b/setup.py
index a634f0b..cfd1c59 100644
--- a/setup.py
+++ b/setup.py
@@ -212,7 +212,8 @@ def link_args():
                 extra_link_args=link_args(),
                 sources=[os.path.join("amplpy", "ampl.pyx")],
             )
-        ], compiler_directives={"language_level": "3", 'binding': True, "embedsignature": True}
+        ], compiler_directives={"language_level": "3", 'binding': True, "embedsignature": True,
+                                "boundscheck": False, "wraparound": False},
     ),
     package_data={"": package_content()},
     install_requires=["ampltools >= 0.7.5"],