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Can Training and Testing PRS in UK Biobank Be Combined to Represent Genetic Risk for All Participants? #19

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laleoarrow opened this issue Dec 14, 2024 · 0 comments
Open

Can Training and Testing PRS in UK Biobank Be Combined to Represent Genetic Risk for All Participants? #19

laleoarrow opened this issue Dec 14, 2024 · 0 comments

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@laleoarrow
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UK Biobank provides polygenic risk scores (PRS) for participants, but some samples are used for training while others are used for testing. Can these two types of PRS be combined to represent the genetic risk scores for all UKB individuals (e.g., to estimate genetic risk for a disease like type 2 diabetes)?
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